Ex Moscow Mayor Yuri Luzhkov: Medvedev 'dictatorial'
In a BBC interview, Mr Luzhkov also criticised preparations for parliamentary elections due in December, predicting fraud.
The former mayor was once one of Russia's most influential politicians but was sacked just over a year ago after falling out with the Kremlin.
The Russian authorities have since accused him and his wife of corruption.
He said December's vote would not be free or fair and that regional governors would be under pressure to provide a good result for the governing United Russia party.
He said the party, of which he was once a high-ranking member, would not be able to win the elections without a massive fraud.
"There's no competition; there are no alternatives to choose from," he said.
"Unfortunately we already know the outcome and we know who will be governing Russia next year."
Mr Medvedev, who has held the presidency since 2008, is widely expected to become prime minister.
Mr Luzhkov considers Prime Minister Vladimir Putin, who is likely to become Russia's next leader in presidential elections, the more democratic face of the ruling duo in the Kremlin.
"Despite the fact that Putin is widely regarded in the West as less democratic than Medvedev, in fact Putin is more tolerant towards any sort of dissent," he said
"Medvedev shows inclinations to suppress any dissent," he said. "Medvedev would make as inefficient a prime-minister of Russia as he was a president."
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